Dr. Simone Macrí
The Istituto Superiore di Sanità (ISS, Italian National Institute of Health) is the major Italian institution devoted to Public Health. The ISS constitutes the technical and scientific counterpart of the Italian Ministry of Health. Its major role within the project will be the development and validation of mouse models of insulin-related comorbidities. These activities will be conducted at the Centre for Behavioural Sciences and Mental Health which has been working for decades on alterations of individual developmental trajectories as a function of environmental, genetic, and pharmacological factors. The ISS will first identify experimental models exhibiting behavioural and physiological alterations analogous to those observed in the human cohorts and then investigate the therapeutic potentials of drugs acting on insulin pathways.
ISS declares no conflict of interest in PRIME.