Publications

2024

• Baenas I, Camacho‐Barcia L, Granero R. et al. Association between type 2 diabetes and depressive symptoms after a 1‐year follow‐up in an older adult Mediterranean population. J Endocrinol Invest 47, 1405–1418 (2024).
• Beck C, Pedersen CB, Plana‐Ripoll O, et al. A comprehensive analysis of age of onset and cumulative incidence of mental disorders: A Danish register study. Acta Psychiatr Scand. Volume 149, Issue 6 (2024) 467-478.
• Bruckner F, Gruber JR, Ruf A, Edwin Thanarajah S, Reif A, Matura S. Exploring the Link between Lifestyle, Inflammation, and Insulin Resistance through an Improved Healthy Living Index. Nutrients Volume 16, Issue 3 (2024) 388.
• Chatwin H, Holde K, Wimberley T et al. Parental psychopathology before and after the child’s diagnosis of a mental disorder: a population‐based matched cohort study. J Child Psychol Psychiatry, in press (2024).
• Fanelli G, Franke B, Fabbri C, Werme J, Erdogan I, De Witte W, Poelmans G, Ruisch IH, Reus LM, van Gils V, Jansen WJ, Vos SJB, Alam KA, Martinez A, Haavik J, Wimberley T, Dalsgaard S, Fóthi Á, Barta C, Fernandez‐Aranda F, Jimenez‐Murcia S, Berkel S, Matura S, Salas‐Salvadó J, Arenella M, Serretti A, Mota NR, and Bralten J. Local patterns of genetic sharing challenge the boundaries between neuropsychiatric and insulin resistance‐related conditions. medRxiv (2024) 2024.03.07.24303921.
• Gómez‐Martínez C, Babio N, Camacho‐Barcia L et al. Glycated hemoglobin, type 2 diabetes, and poor diabetes control are positively associated with impulsivity changes in aged individuals with overweight or obesity and metabolic syndrome. Ann NY Acad Sci, in press (2024).
• Gruber JR, Ruf A, Süß ED et al. Impact of blood glucose on cognitive function in insulin resistance: novel insights from ambulatory assessment. Nutr Diabetes 14, 200–209 (2024).
• Gutierrez-Tordera L, Papandreou C, Novau-Ferré N et al. Exploring small non-coding RNAs as blood-based biomarkers to predict Alzheimer’s disease. Cell & Bioscience Volume 14 (2024).
• Jakobi B, Vlaming P, Mulder D et al. The gut‐microbiome in adult Attention‐deficit/hyperactivity disorder – A Meta‐analysis. Eur Neuropsychopharmacol 88, 10–20 (2024).
• Konstanti P, Gómez-Martínez C, Muralidharan J et al. Faecal microbiota composition and impulsivity in a cohort of older adults with metabolic syndrome. Sci Rep 14, 78527 (2024).
• Macrì S, Laviola G. Can we target insulin signalling for cognition therapeutics? Expert Opin Ther Targets 28, 100–108 (2024).
• Presta M, Zoratto F, Mulder D, Ottomana AM, Pisa E, Arias Vásquez A, Slattery DA, Glennon JC and Macrì S. Hyperglycemia and cognitive impairments anticipate the onset of an overt type 2 diabetes‐like phenotype in TALLYHO/JngJ mice. Psychoneuroendocrinology Volume 167 (2024) 107102.
• Rojas-Criollo M, Novau-Ferré N, Gutierrez-Tordera L, Ettcheto M, Folch J, Papandreou C, Panisello L, Cano A, Mostafa H, Mateu-Fabregat J, et al. Effects of a High-Fat Diet on Insulin-Related miRNAs in Plasma and Brain Tissue in APPSwe/PS1dE9 and Wild-Type C57BL/6J Mice. Nutrients Volume 16, Issue 7(2024) 955.
• Ruisch IH, Widomska J, De Witte W et al. Molecular landscape of the overlap between Alzheimer’s disease and somatic insulin-related diseases. Alz Res Ther 16, 50–60 (2024).
• Segal A, Smith RE, Chopra S et al. Multiscale heterogeneity of white matter morphometry in psychiatric disorders. bioRxiv preprint (2024).
• van Gils V, Tao Q, Ang TF et al. Associations Between Glucose Metabolism Measures and Amyloid-β and Tau Load on PET 14 Years Later: Findings From the Framingham Heart Study. Diabetes Care 47, 100–108 (2024).
• van Gils V, Rizzo M, Côté J, Viechtbauer W, Fanelli G, Salas-Salvadó J, Wimberley T, Bulló M, Fernandez-Aranda F, Dalsgaard S, Visser PJ, Jansen WJ, and Vos SJB. The association of glucose metabolism measures and diabetes status with Alzheimer’s disease biomarkers of amyloid and tau: A systematic review and meta‐analysis. Neuroscience & Biobehavioral Reviews Volume 159 (2024) 105604.
• van Gils, V. The role of diabetes and vascular burden in Alzheimer’s disease: a pathophysiological perspective. Doctoral Thesis, Maastricht University (2024).
• Wimberley T, Brikell I, Astrup A, et al. Shared familial risk for type 2 diabetes mellitus and psychiatric disorders: a nationwide multigenerational genetics study. Psychological Medicine Volume 54, Issue 11 (2024) 2976-2985.
• Yu Y, Cui H‑Q, Haas SS et al. Brain‐age prediction: Systematic evaluation of site effects, and sample age range and size. Hum Brain Mapp 45, 300–312 (2024).

2023

• Alam K, Svalastoga P, Martinez A, Glennon J and Haavik J. Potassium channels in behavioral brain disorders. Molecular mechanisms and therapeutic potential: A narrative review. Neuroscience & Biobehavioral Reviews Volume 152 (2023) 105301.
• Arenella M, Mota NR, Teunissen MWA et al. Autism spectrum disorder and brain volume link through a set of mTOR‐related genes. J Child Psychol Psychiatry 64, 1234–1242 (2023).
• Arenella M, Fanelli G, Kiemeney LA et al. Genetic relationship between the immune system and autism. Brain Behav Immun Health 34, 100698 (2023).
• Ayala-Rojas R‑E, Granero R, Fernández-Aranda F et al. Online Gaming Disorder and Sports Betting Addiction: Convergences and Divergences. Int J Ment Health Addict, in press (2023).
• Brikell I, Wimberley T, Albiñana C, et al. Interplay of ADHD Polygenic Liability With Birth-Related, Somatic, and Psychosocial Factors in ADHD: A Nationwide Study. American Journal of Psychiatry Volume 180, Issue 1 (2023) 73-88.
• Cabana-Domínguez J, Antón-Galindo E, Fernàndez-Castillo N, Singgih E L, O’Leary A, Norton W HG, Strekalova T, Schenck A, Reif A, Lesch K-P, Slattery D and Cormand B. The translational genetics of ADHD and related phenotypes in model organisms. Neuroscience & Biobehavioral Reviews Volume 144 (2023) 104949.
• Espinosa-Jiménez T, Cano A, Sánchez-López E. et al. A novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimer’s disease exacerbated with high fat diet. Cell Biosci 13, 52 (2023).
• Gruber J, Hanssen R, Qubad M, Bouzouina A, Schack V, Sochor H, Schiweck C, Aichholzer M, Matura S, Slattery D, Zopf Y, Borgland S, Reif A and Thanarajah S. Impact of insulin and insulin resistance on brain dopamine signalling and reward processing – An underexplored mechanism in the pathophysiology of depression? Neuroscience & Biobehavioral Reviews Volume 149 (2023) 105179.
• Lucas I, Granero R, Mora-Maltas B et al. Rethinking cutoff values for the South Oaks Gambling Screen: Sex-specific insights and DSM-5 severity adjustments in Gambling Disorder assessment. J Behav Addict 13, 45–53 (2023).
• Ni J, Nishi SK, Babio N, Ros E, Basterra-Gortari FJ, Corella D, Castañer O, Martínez JA, Alonso-Gómez ÁM, Wärnberg J, Vioque J, Romaguera D, López-Miranda J, Estruch R, Tinahones FJ, Santos-Lozano JM, Serra-Majem L, Cano-Ibáñez N, Tur JA, Fernández-García JM, Pintó X, Delgado-Rodríguez M, Matía-Martín P, Vidal J, Vázquez C, Daimiel L, Fernández-Aranda F, Ruiz-Canela M, Mestres Solà C, Portolés O, Sala-Vila A, Garcia-Rios A, Compañ-Gabucio LM, Gómez-Gracia E, Zulet MA, Chaplin A, Casas R, Martínez-Diz S, Tojal-Sierra L, Gómez-Pérez AM, Toledo E, Rios S, Ortega-Azorín C, de la Torre R, Peña-Orihuela PJ, Garcia-de la Hera M, Sayón-Orea C, Malcampo M and Salas-Salvadó J. Higher versus lower nut consumption and changes in cognitive performance over two years in a population at risk of cognitive decline: a cohort study. The American Journal of Clinical Nutrition Volume 118, Issue 2 (2023) 360-368.
• Nishi, S.K., Babio, N., Paz-Graniel, I. et al. Water intake, hydration status and 2-year changes in cognitive performance: a prospective cohort study. BMC Medicine 21 (2023).
• Ottomana AM, Presta M, O’Leary A, Sullivan M, Pisa E, Laviola G, Glennon JC, Zoratto F, Slattery DA, Macrì S. A systematic review of preclinical studies exploring the role of insulin signalling in executive function and memory. Neuroscience & Biobehavioral Reviews Volume 155 (2023) 105435.
• Possidente C, Fanelli G, Serretti A and Fabbri C. Clinical insights into the cross-link between mood disorders and type 2 diabetes: A review of longitudinal studies and Mendelian randomisation analyses. Neuroscience & Biobehavioral Reviews Volume 152 (2023) 105298.
• Réthelyi JM, Vincze K, Schall D, Glennon J, Berkel S. The role of insulin/IGF1 signalling in neurodevelopmental and neuropsychiatric disorders – Evidence from human neuronal cell models. Neuroscience & Biobehavioral Reviews Volume 153 (2023) 105330.
• Shi Y, Sprooten E, Mulders P et al. Multi‐polygenic scores in psychiatry: From disorder specific to transdiagnostic perspectives. Am J Med Genet B Neuropsychiatr Genet 195, 159–168 (2023).
• Sullivan M, Fernandez-Aranda F, Camacho-Barcia L, Harkin A, Macrì S, Mora-Maltas B, Jiménez-Murcia S, O’Leary A, Ottomana A, Presta M, Slattery D, Scholtz S and Glennon J. Insulin and disorders of behavioural flexibility. Neuroscience & Biobehavioral Reviews Volume 150 (2023) 105169.
• Zoratto, F., Pisa, E., Soldati, C. et al. Automation at the service of the study of executive functions in preclinical models. Sci Rep 13, 16890 (2023).

2022

• Fanelli G, Franke B, De Witte W, Ruisch IH, Haavik J, van Gils V, Jansen WJ, Vos JBS, Lind L, Buitelaar JK, Tobias Banaschewski T, Søren Dalsgaard S, Alessandro Serretti A, Nina Roth Mota N, Geert Poelmans G, Janita Bralten J. Insulinopathies of the brain? Genetic overlap between somatic insulin-related and neuropsychiatric disorders. Transl Psychiatry (2022) 12, 59.
• Fanelli G, Roth Mota N, Salas-Salvadó J, Fernández-Aranda F, Testa G, Jiménez-Murcia S, Bertaina-Anglade V, Camacho-Barcia L, Poelmans G, van Gils V, Jansen WJ, Vos JBS, Wimberley T, Dalsgaard S, Barta C, Serretti A, Bralten J. The link between cognition and somatic conditions related to insulin resistance in the UK Biobank study cohort: a systematic review. Neuroscience and Biobehavioral Reviews Volume 143 (2022) 104927. Read a summary of the article here.
• Gómez-Martínez, C., Babio, N., Júlvez, J. et al. Impulsivity is longitudinally associated with healthy and unhealthy dietary patterns in individuals with overweight or obesity and metabolic syndrome within the framework of the PREDIMED-Plus trial. Int J Behav Nutr Phys Act 19, 101 (2022).
• Martín-Peláez S, Serra-Majem L, Cano-Ibáñez N, Martínez-González MÁ, Salas-Salvadó J, Corella D, Lassale C, Martínez JA, Alonso-Gómez ÁM, Wärnberg J, Vioque J, Romaguera D, López-Miranda J, Estruch R, Tinahones FJ, Lapetra J, Fernández-Aranda F, Bueno-Cavanillas A, Tur JA, Martín V, Pintó X, Delgado-Rodríguez M, Matía P, Vidal J, Vázquez C, Daimiel L, Ros E, Toledo E, Nishi SK, Sorli JV, Malcampo M, Zulet MÁ, Moreno-Rodríguez A, Cueto-Galán R, Vivancos-Aparicio D, Colom A, García-Ríos A, Casas R, Bernal-López MR, Santos-Lozano JM, Vázquez Z, Gómez-Martínez C, Ortega-Azorín C, Del Val JL, Abete I, Goikoetxea-Bahon A, Pascual E, Becerra-Tomás N, Chillarón JJ, Sánchez-Villegas A. Contribution of cardio-vascular risk factors to depressive status in the PREDIMED-PLUS Trial. A cross-sectional and a 2-year longitudinal study. PLoS One (2022) 17(4):e0265079.
• Ni et al. Dairy Product Consumption and Changes in Cognitive Performance: Two-Year Analysis of the PREDIMED-Plus Cohort. Molecular Nutrition and Food Research (2022) 66 (14). Read a summary of the article here.
• Sonuga-Barke E J S, Becker S P, Bölte S, Castellanos F X, Franke B, Newcorn J H, Nigg J T, Rohde L A and Simonoff E. Annual Research Review: Perspectives on progress in ADHD science – from characterization to cause. Journal of Child Psychology and Psychiatry (2022) 0021-9630.
• Testa et al. Impulsive personality traits predicted weight loss in individuals with type 2 diabetes after 3 years of lifestyle interventions. Journal of Clinical Medicine (2022) 11 (12), 3476. Read a summary of the article here.
• Wimberley T, Horsdal HT, Brikell I, Laursen TM, Astrup A, Fanelli G, Bralten J, Poelmans G, Van Gils V, Jansen WJ, Vos SJB, Bertaina-Anglade V, Camacho-Barcia L, Mora-Maltas B, Fernandez-Aranda F, Bonet MB, Salas-Salvadó J, Franke B, Dalsgaard S. Temporally ordered associations between Type 2 Diabetes and Brain Disorders – a Danish Register-Based Cohort Study. BMC Psychiatry (2022) 22, 573.

2021

• Camacho-Barcia, L.; Munguía, L.; Lucas, I.; de la Torre, R.; Salas-Salvadó, J.; Pintó, X.; Corella, D.; Granero, R.; Jiménez-Murcia, S.; González-Monje, I.; Esteve-Luque, V.; Cuenca-Royo, A.; Gómez-Martínez, C.; Paz-Graniel, I.; Forcano, L.; Fernández-Aranda, F. Metabolic, Affective and Neurocognitive Characterization of Metabolic Syndrome Patients with and without Food Addiction. Implications for Weight Progression. Nutrients (2021) 13, 2779.
• Gómez-Martínez C, Babio N, Júlvez J, Becerra-Tomás N, Martínez-Gonzá lez MÁ, Corella D, Castañer O, Romaguera D, Vioque J, Alonso-Gómez ÀM, Wärnberg J, Martínez JA, Serra-Majem L, Estruch R, Tinahones FJ, Lapetra J, Pintó X, Tur JA, López-Miranda J, Bueno-Cavanillas A, Gaforio JJ, Matía-Martín P, Daimiel L, Martín-Sánchez V, Vidal J, Vázquez C, Ros E, Dalsgaard S, Sayón-Orea C, Sorlí JV, de la Torre R, Abete I, Tojal-Sierra L, Barón-López FJ, Fernández-Brufal N, Konieczna J, García-Ríos A, Sacanella E, Bernal-López MR, Santos-Lozano JM, Razquin C, Alvarez-Sala A, Goday A, Zulet MA, Vaquero-Luna J, Diez-Espino J, Cuenca-Royo A, Fernández-Aranda F, Bulló M and Salas-Salvadó J on behalf of the PREDIMED-Plus Investigators. Glycemic Dysregulations Are Associated With Worsening Cognitive Function in Older Participants at High Risk of Cardiovascular Disease: Two-Year Follow-up in the PREDIMED-Plus Study. Frontiers in Endocrinology (2021) 754347.
• Mallorquí‑Bagué N, Lozano‑Madrid M, Vintró‑Alcaraz C, Forcano L, Díaz‑López A, Galera A, Fernández‑Carrión R, Granero R, Jiménez‑Murcia S, Corella D, Pintó X, Cuenca‑Royo A, Bulló M, Salas‑Salvadó J, de la Torre R, Fernández‑Aranda F. Effects of a psychosocial intervention at one‑year follow‑up in a PREDIMED‑plus sample with obesity and metabolic syndrome. Scientific Reports (2021) 11:9144.
• Martin J, Khramtsova E, Goleva S, Blokland G, Traglia M, Walters R, Hübel C, Coleman J, Breen G, Børglum A,  Demontis D, Grove J, Werge T, Bralten J, Bulik C, Lee P, Mathews C, Peterson R, Winham S, Wray N, Edenberg H, Guo W, Yao Y, Neale B, Faraone S, Petryshen T, Weiss L, Duncan L, Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium, Goldstein J, Smoller J, Stranger B, Davis L. Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits. Biological Psychiatry (2021) 89:1127-1137.
• Munguía L,Jiménez-Murcia S, Granero R, Baenas I, Agüera Z, Sánchez I, Codina E, del Pino-Gutiérrez A, Testa G, Treasure J and Fernández-Aranda F. Emotional regulation in eating disorders and gambling disorder: A transdiagnostic approach. Journal of Behavioral Addictions (2021) 508-523.
• Nishi SK, Babio N, Gómez-Martínez C, Martínez-González MÁ, Ros E, Corella D, Castañer O, Martínez JA, Alonso-Gómez ÁM, Wärnberg J, Vioque J, Romaguera D, López-Miranda J, Estruch R, Tinahones FJ, Lapetra J, Serra-Majem JL, Bueno-Cavanillas A, Tur JA, Martín Sánchez V, Pintó X, Delgado-Rodríguez M, Matía-Martín P, Vidal J, Vázquez C, Daimiel L, Razquin C, Coltell O, Becerra-Tomás N, De La Torre Fornell R, Abete I, Sorto-Sanchez C, Barón-López FJ, Signes-Pastor AJ, Konieczna J, Garcia-Rios A, Casas R, Gomez-Perez AM, Santos-Lozano JM, García-Arellano A, Guillem-Saiz P, Ni J, Trinidad Soria-Florido M, Zulet MÁ, Vaquero-Luna J, Toledo E, Fitó M, Salas-Salvadó J. Mediterranean, DASH, and MIND Dietary Patterns and Cognitive Function: The 2-Year Longitudinal Changes in an Older Spanish Cohort. Front. Aging Neurosci (2021) 13.
• Soldevila-Domenech N, Cuenca-Royo A M, Babio N, Forcano L, Nishi S, Vintró C, Gómez-Martínez C, Jiménez-Murcia S, Fernández-Carrión R, González M G, Alvarez-Sala A, Carlos S, Pinto X, Corella D, Díez-Espino J, Castañer O, Fernández-Aranda F, Salas-Salvadó J and de la Torre R. Metformin Use and Cognitive Function in Older Adults With Type 2 Diabetes Following a Mediterranean Diet Intervention. Frontiers in Nutrition (2021) 8:742586.
• Soldevila-Domenech N, Forcano L, Vintró C, Cuenca-Royo A M, Pinto X, Jiménez-Murcia S, García-Gavilán J F, Nishi S, Babio N, Gomis-González M, Corella D, Sorlí J V, Fernandez-Carrión R, Martínez-González M A, Marti A, Salas-Salvadó J, Castañer O, Fernandez-Aranda F and de la Torre R. Interplay between cognition and weight reduction in individuals following a Mediterranean Diet: Three-year follow-up of the PREDIMED-Plus trial. Clinical nutrition (2021) 40(9):5221-5237.
• Testa G, Mora-Maltas B, Camacho-Barcia L, Granero R, Lucas I, Agüera Z, Jiménez-Murcia S, Baños R, Bertaina-Anglade V, Botella C, Bulló M, Casanueva FF, Dalsgaard S, Fernández-Real JM, Franke B, Frühbeck G, Fitó M, Gómez-Martínez C, Pintó X, Poelmans G, Tinahones FJ, Torre R, Salas-Salvadó J, Serra-Majem L, Vos S, Wimberley T, Fernández-Aranda F. Transdiagnostic Perspective of Impulsivity and Compulsivity in Obesity: From Cognitive Profile to Self-Reported Dimensions in Clinical Samples with and without Diabetes. Nutrients (2021) 13, 4426. Read a summary of the article here.
• Tielbeek J J,Uffelmann E, Williams B S, Colodro-Conde L, Gagnon É, Mallard T T, Levitt B, Jansen P R, Johansson A, Sallis H, Pistis G, Saunders G R B, Allegrini A G, Rimfeld K, Konte B, Klein M, Hartmann A M, Salvatore J E, Nolte I M, Demontis D, Malmberg A, Burt S A, Savage J, Sugden K,Poulton R, Harris K M, Vrieze S, McGue M, Iacono W G, Mota N R, Mill J, Viana J F, Mitchell B L, Morosoli J J, Andlauer T, Ouellet-Morin I, Tremblay R E, Côté S, Gouin J-P, Brendgen M, Dionne G, Vitaro F, Lupton M K, Martin N G, Räikkönen K, Eriksson J, Lahti J, Hartman C A, Oldehinkel A J, Snieder H, Liu H, Preisig M, Whipp A, Vuoksimaa E, Lu Y, Jern P, Rujescu D, Giegling I, Palviainen T, Kaprio J, Harden K P, Munafò M R, Morneau-Vaillancourt G, Plomin R, Viding E, Boutwell B, Aliev F, Dick D, Popma A, Faraone S V, Børglum A, Medland S E, Franke B, Boivin M, Pingault J-P, Glennon J C, Barnes J C, Fisher S E, Moffitt T E, Caspi A, Polderman T JC and Posthuma D. Uncovering the Genetic Architecture of Broad Antisocial Behavior through a Genome-Wide Association Study Meta-analysis. bioRxiv (2021).

2020

• Bralten J,  Widomska J, De Witte W, Yu D, Mathews CA, Scharf JM, Buitelaar J, Crosbie J, Schachar R, Arnold P, Lemire M, Burton CL, Franke B and Poelmans G. Shared genetic etiology between obsessive-compulsive disorder, obsessive-compulsive symptoms in the population, and insulin signaling. l. Translational Psychiatry (2020) 10:121.
• Fanelli G, Barbara F, De Witte W, Mota N R, Poelmans G, Bralten J. Genetic overlap between somatic insulin-related and neuro-psychiatric disorders. European Neuropsychopharmacology (2020) Volume 40, Supplement 1, Pages S97-S98.